Pore performance
نویسندگان
چکیده
منابع مشابه
Imaging β amyloid's pore performance
A lzheimer's disease (AD) is triggered by the inappropriate processing of amyloid precursor protein to generate excess amounts of short peptide fragments called  amyloid (A). For many years, the neurodegeneration associated with AD was thought to be caused by the aggregation of A into insoluble, fi brous plaques. However, increasing suspicion now falls on smaller, soluble A oligomers as the...
متن کاملEffect of pore size on the performance of immobilised enzymes.
Porous materials are widely employed as supports in the immobilisation of enzymes. Traditionally macroporous materials with pore diameters >50 nm were believed to be the most suitable support material, ensuring no spatial restrictions upon enzyme molecules entering such large pores. In recent years however, there has been growing emphasis in the use of mesoporous supports with pore diameters ra...
متن کاملPore relations: nuclear pore complexes and nucleocytoplasmic exchange.
NPCs are the sole sites of exchange between the nucleus and cytoplasm. A large family of transport factors carry cargo between the nucleus and cytoplasm through the NPC. The NPC is a huge symmetric octagonal structure comprised of dozens of NUPs. NUPs make many contacts with surrounding structures, including the NE, the cytoplasm and nuclear interior. A subset of NUPs contain repeated peptide m...
متن کاملCilia and Nuclear Pore Proteins: Pore No More?
Nuclear pore proteins at the base of cilia were thought to regulate transport into cilia. In this issue of Developmental Cell, Del Viso et al. (2016) challenge this view, showing instead that pore proteins localize to ciliary basal bodies and that their perturbation leads to congenital heart disease.
متن کاملA complex of nuclear pore proteins required for pore function
A family of proteins bearing novel N-acetylglucosamine residues has previously been found to be required to form functional nuclear pores. To begin to determine which of the proteins in this family are essential for pore function, antisera were raised to each of three members of the family, p62, p58, and p54. With these antisera, it was possible to deplete nuclear reconstitution extracts of the...
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2001
ISSN: 1471-0072,1471-0080
DOI: 10.1038/35052044